Over the past 20 years the use of negative pressure wound therapy (NPWT) has broadened and is now widely used in the management of complex wounds in a range of settings. Trauma and pain caused by the removal and reapplication of NPWT dressings has been identified as a major contributor to wound pain. Film-based dressings with adhesive skin contact layers are used to keep NPWT systems in place and skin stripping may occur because the film can adhere too aggressively to the periwound skin, resulting in trauma and pain on removal. Here, the authors report 10 patients’ responses to a questionnaire on the experiences of dressing changes using a traditional acrylic adhesivebased film (Avance® Film; Mölnlycke Health Care) or an advanced silicone adhesivebased film (Avance® Film with Safetac®; Mölnlycke Health Care) during treatment with NPWT. Overall, the patients were satisfied with the silicone adhesive-based film and preferred it to the acrylic adhesive-based film.