Journal Articles

Amelogenin: extracellular matrix protein for the treatment of hard-to-heal wounds

Share this article

Amelogenin: extracellular matrix protein for the treatment of hard-to-heal wounds

Marco Romanelli
31 May 2010

Amelogenin is an extracellular matrix protein with biological activity in the regeneration of the periodontium and repair of the skin. Recent published studies have highlighted the use of Xelma® (Mölnlycke Health Care AB, Göteborg, Sweden) in the treatment of hard-to-heal wounds, such as venous leg ulcers. This article reviews the literature relating to the cellular interactions of amelogenin and collates the clinical and health economic data relating to clinical and health economic studies involving patients with chronic wounds. It also discusses a hypothetical mechanism of action of amelogenin in the healing of such wounds.

Free for all healthcare professionals

Sign up to the Wounds Group journals





By clicking ‘Subscribe’, you are agreeing that the Wounds Group are able to email you periodic newsletters. You may unsubscribe from these at any time. Your info is safe with us and we will never sell or trade your details. For information please review our privacy policy.

Are you a healthcare professional? This website is for healthcare professionals only. To continue, please confirm that you are a healthcare professional below.

We use cookies responsibly to ensure that we give you the best experience on our website. If you continue without changing your browser settings, we’ll assume that you are happy to receive all cookies on this website. Read about how we use cookies.

I am not a healthcare professional.